R H2O_y = exp[-TE/T2 W_y ] (1 exp[-TR/T1 W_y ]) is used to compute the relaxation attenuation factors with T1 W_y and T2 W_y being the T1 and T2 relaxation durations of water in compartment y (i.e., GM, WM, or CSF)
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Despite promising preliminary findings, several research gaps remain
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& Gan, W.-B